Hours Jersey Mike's Subs - Main Street, Columbus, OH
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Holiday Hours 2026 Show
Christmas Day
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Jersey Mike's Subs occupies a prime position at 2480 E Main Street, within the east region of Columbus (by E Main St & Euclaire Ave). The restaurant is an outstanding addition to the local businesses of Blacklick, Brice, Grove City, Westerville, Groveport, Reynoldsburg and Summit Station. If you'd like to swing by today (Sunday), it's open from 10:00 am to 9:00 pm. Please see this page for other information regarding Jersey Mike's Subs Main Street, Columbus, OH, including the business hours, address or customer experience.
Visit your local Jersey Mike's Subs branch in the vicinity of the intersection of South Cassingham Road and East Main Street, in Columbus, Ohio.
The restaurant is conveniently located a 1 minute drive time from South Cassady Avenue, Exit 103 A (East Freeway) of I-70, East Mound Street and Bryden Road; a 5 minute drive from College Avenue, South Drexel Avenue (US-40) or East Main Street (US-40); and a 12 minute drive time from East Freeway (I-70) or North Nelson Road (US-62).
For GPS units the address is 2480 E Main Street, Columbus, OH 43209.
You can catch the buses to East Main Street & Euclaire Avenue. The best route to get here is 2.
If traveling by foot you may come across Havenwood Park, Pump House Park, Bexley Football Field, Bexley Public Library and Bernlohr Stadium.
Including this restaurant, Jersey Mike's Subs now owns 5 locations in Columbus, Ohio.
Click here for a complete listing of Jersey Mike's Subs branches near Columbus.
