CVS Pharmacy - South Main Street, Orange, CA

480 South Main StreetOrangeCA 92868
Today: 24 hours

Hours CVS Pharmacy - South Main Street, Orange, CA

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday

Holiday Hours 2026 Show

Good Friday
Easter Saturday
Easter Sunday
Easter Monday
Christmas Eve
Christmas Day
Boxing Day
New Year’s Eve
New Year’s Day
Columbus Day
Independence Day
Juneteenth
Labor Day
Thanksgiving Day
Veterans Day

Photo Hours

Monday24 hours

Pharmacy

Monday24 hours

Monday - Sunday: Closed for lunch 13:30 - 14:00

CVS Pharmacy Easter Opening Hours 2026

CVS retail stores operate normally on Easter Sunday, though specific pharmacy counters may have modified hours. Regular business hours resume across the board on Good Friday, Saturday, and Monday.

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Customer rating
3(1x)
051

CVS Pharmacy - South Main Street, Orange, CA - Hours & Store Details


CVS Pharmacy Store is located within easy reach at 480 South Main Street, within the south-west section of Orange (near to La Veta-Main). The store serves patrons from the districts of Garden Grove, Villa Park, Santa Ana, Anaheim, Tustin, Fountain Valley and Atwood. For your convenience, its hours of operation last today (Monday) around-the-clock. On this page you may find all the up-to-date information about CVS Pharmacy South Main Street, Orange, CA, including the operating hours, location info, email contact, and more info.


CVS Pharmacy Store is located in the vicinity of the intersection of West Providence Avenue and South Main Street, in Orange, California.

By car

1 minute drive from Exit 14B (Garden Grove Freeway) of Ca-22, West Culver Avenue, La Veta Avenue or South Bedford Road; a 5 minute drive from Garden Grove Freeway (Ca-22), Santa Ana Freeway (I-5) and Exit 106 (Santa Ana Freeway) of I-5; and a 9 minute drive time from Orange Freeway (Ca-57) and Exit 1B (Orange Freeway) of Ca-57.

For patrons using navigation systems to get to this location, enter this address: 480 South Main Street, Orange, CA 92868.

By bus

Buses can be caught at Main-La Veta, Main-Culver, La Veta-Main and La Veta-Pepper. You can choose from services: 53, 83 or 453.

By train

If you're coming by train, you can alight at Orange Station (4640 ft), Anaheim Station (1.76 mi) and Santa Ana Station (2.34 mi away). These lines will bring you here: Inland Empire–Orange County and Orange County.

On foot

Within a couple miles you'll come across MainPlace Mall, Saint Joseph Hospital, Children's Hospital of Orange County, West Orange Elementary School, William Eldridge Park and Santiago Park.


The total number of CVS Pharmacy locations presently open in Orange, California is 6.

Go to this link with an entire directory of CVS Pharmacy locations near Orange.

Open: 7:00 am - 1:00 am0.03mi
Open: 5:30 am - 5:30 pm0.18mi
Open: 10:00 am - 10:00 pm0.20mi